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Many of our preconceived notions about immigrants likely bear very little resemblance to the facts.

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Astronomers have discovered a remarkable star system just 150 light-years from Earth that's destined for a spectacular cosmic display. The system contains a white dwarf star drawing material from its companion star, with the pair orbiting at just 1/60th of the Earth-Sun distance. With their combined mass reaching 1.56 times that of our Sun, these stars are gradually spiralling toward each other, setting the stage for a spectacular explosion. Fortunately, scientists estimate this cataclysmic event won't occur for roughly 23 billion years, long after our own Sun will have reached the end of its life cycle.

A study reveals that termites are not simply spreading through natural processes, suggesting humans may be helping them 'conquer the world' by unknowingly transporting them aboard private boats.

Scientists have developed an artificial intelligence-based method to more accurately detect antibiotic resistance in deadly bacteria such as tuberculosis and staph. The breakthrough could lead to faster and more effective treatments and help mitigate the rise of drug-resistant infections, a growing global health crisis.

The world is littered with trillions of micro- and nanoscopic pieces of plastic. These can be smaller than a virus -- just the right size to disrupt cells and even alter DNA. Researchers find them almost everywhere they've looked, from Antarctic snow to human blood. In a new study, scientists have delineated the molecular process that causes these small pieces to break off in such large quantities.

A web platform uses a chatbot to enable any chemist -- including undergraduate chemistry majors -- to configure and execute complex quantum mechanical simulations through chatting.

A web platform uses a chatbot to enable any chemist -- including undergraduate chemistry majors -- to configure and execute complex quantum mechanical simulations through chatting.

Despite its uniquely rich inventory of organic molecules, Saturn's largest moon, Titan, may be able to support only a minuscule amount of biomass, if life exists on the moon, according to a study using bioenergetic modeling.

Although astronomers have ruled out a smash-up between Earth and an asteroid known as 2024 YR4 in the year 2032, the building-sized space rock still has a chance of hitting the moon. In fact, the chances — slight as they are — have doubled in the past month.

Despite their name, black holes can sometimes emit radiation. A team of astronomers has recently detected a flicker of X-ray radiation from the supermassive black hole at the center of the Andromeda Galaxy. This flicker was identified using 15 years of data from the Chandra X-ray Observatory, revealing two distinct flashes in 2006 and 2013. Interestingly, these flashes coincided with bursts of neutrinos detected by the IceCube Neutrino Observatory, offering exciting new insights into the extreme conditions surrounding the black hole.

Terraforming Mars has been the long-term dream of colonization enthusiasts for decades. But when you start to grapple with the actual physics of what would be necessary to do so, the effort seems further and further out of reach. Depictions like those of Kim Stanley Robinson's Mars Trilogy are just wildly unrealistic regarding the sheer amount of material that must be moved to the Red Planet to achieve anything remotely resembling Earth-like conditions. That is the conclusion of an abstract presented at the 56th Lunar and Planetary Science Conference by Leszek Czechowski of the Polish Academy of Sciences.

What if we spend decades building advanced telescopes to search for life on other planets and come up emptyhanded? A recent study exploring what we can learn about life in the universe -- even if we don't detect signs of life or habitability. Using advanced statistical modeling, the research team sought to explore how many exoplanets scientists should observe and understand before declaring that life beyond Earth is either common or rare.

Tariff policy has been a contentious issue since the founding of the United States. Hamilton clashed with Jefferson and Madison over tariff policy in the 1790s, South Carolina threatened to secede from the union over tariff policy in 1832, and the Hawley-Smoot tariff generated outrage in 1930. Currently, Trump is sparking heated debates about his tariff policies. 

To understand the ongoing tariff debate, it is essential to grasp the basics: Tariffs are taxes levied by governments on imported goods. They have been the central focus of U.S. trade policy since the federal government was established in 1789. Historically, tariffs have been used to raise government revenue, protect domestic industries, and influence the trade policies of other nations. The history of U.S. tariffs can be understood in three periods corresponding with these three uses. 

From 1790 until the Civil War in 1861, tariffs primarily served as a source of federal revenue, accounting for about 90 percent of government income (since 2000, however, tariffs have generated less than 2 percent of the federal government’s income).1 Both the Union and the Confederacy enacted income taxes to help finance the Civil War. After the war, public resistance to income taxes grew, and Congress repealed the federal income tax in 1872. Later, when Congress attempted to reinstate an income tax in 1894, the Supreme Court struck it down in Pollock v. Farmers’ Loan & Trust Co. (1895), ruling it unconstitutional. To resolve this issue, the Sixteenth Amendment was ratified in 1913, granting Congress the authority to levy income taxes. Since then, federal income taxes have provided a much larger source of revenue than tariffs, allowing for greater federal government expenditures. The shift away from tariffs as the primary revenue source began during the Civil War and was further accelerated by World War I, which required large increases in federal spending.

The 16th Amendment was ratified in 1913, granting Congress the authority to levy income taxes.

Before the Civil War, the North and South had conflicting views on tariffs. The North, with its large manufacturing base, wanted higher tariffs to protect domestic industries from foreign competition. This protection would decrease the amount of competition Northern manufacturers faced, allowing them to charge higher prices and encounter less risk of being pushed out of business by more efficient foreign producers. By contrast, the South, with an economy rooted in agricultural exports (especially cotton) favored low tariffs, as they benefited from cheaper imported manufactured goods. These imports were largely financed by selling Southern cotton, produced by enslaved labor, to foreign markets, particularly Great Britain. The North-South tariff divide eventually led to the era of protective tariffs (1860-1934) after the Civil War, when the victorious North gained political power, and protectionist policies dominated U.S. trade.

For more than half a century after the Civil War, U.S. trade policy was dominated by high protectionist tariffs. Republican William McKinley, a strong advocate of high tariffs, won the presidency in 1896 with support from industrial interests. Between 1861 and the early 1930s, average tariff rates on dutiable imports rose to around 50 percent and stayed elevated for decades. As a point of comparison, average tariffs had declined to about 5 percent by the early 21st century. 

Republicans passed the Hawley-Smoot Tariff in 1930, which coincided with the Great Depression. While it is generally agreed among economists that the Hawley-Smoot Tariff did not cause the Great Depression, it further hurt the world economy during the economic downturn (though many observers at the time thought that it was responsible for the global economic collapse). The widely disliked Hawley-Smoot Tariff, along with the catastrophic effects of the Great Depression, allowed the Democrats to gain political control of both Congress and the Presidency in 1932. They passed the Reciprocal Trade Agreements Act (RTAA) in 1934, which gave the president the power to negotiate reciprocal trade agreements. 

The RTAA transitioned some of the power over trade policy, i.e., tariffs, away from Congress and to the President. Whereas the constituencies of specific members of Congress are in certain regions of the U.S., the entire country can vote in Presidential elections. For that reason, regional producers generally have less political power over the President than they do over their specific members of Congress, and therefore the President tends to be less responsive to their interests and more responsive to the interests of consumers and exporters located across the nation. Since consumers and exporters generally benefit from lower tariffs, the President has an incentive to decrease them. Thus, the RTAA contributed to the U.S. lowering tariff barriers around the world. This marked the beginning of the era of reciprocity in U.S. tariff policy (1934-2025) in which the U.S. has generally sought to reduce tariffs worldwide.

World War II and its consequences also pushed the U.S. into the era of reciprocity. The European countries, which had been some of the United States’ strongest economic competitors, were decimated after two World Wars in 30 years. Exports from Europe declined and the U.S. shifted even more toward exporting after the Second World War. As more U.S. firms became larger exporters, their political power was aimed at lowering tariffs rather than raising them. (Domestic companies that compete with imports have an interest in lobbying for higher tariffs, but exporting companies have the opposite interest.)

The World Trade Organization (WTO) was founded in 1995. Photo © WTO.

The end of WWII left the U.S. concerned that yet another World War could erupt if economic conditions were unfavorable around the world. America also sought increased trade to stave off the spread of Communism during the Cold War. These geopolitical motivations led the U.S. to seek increased trade with non-Communist nations, which was partially accomplished by decreasing tariffs. This trend culminated in the creation of the General Agreement on Tariffs and Trade (GATT) in 1947, which was then superseded by the World Trade Organization (WTO) in 1995. These successive organizations helped reduce tariffs and other international trade barriers.

Although there is a strong consensus among economists that tariffs do more harm than good,2,3,4 there are some potential benefits of specific tariff policies.

Pros

1. National Security: In his 1776 classic The Wealth of Nations, Adam Smith acknowledged that trade restrictions could be justified when used to protect industries essential to national defense. In times of war, a nation's wealth is secondary to its security, and tariffs can protect essential industries. However, it is often challenging to determine which industries are truly vital for defense, and some firms have exploited this argument to gain protection, even when their goods are not crucial to national security. 
2. Negotiating Tool: Tariffs can also provide leverage in negotiations. For example, in early 2025, President Trump threatened Mexico and Canada with tariffs, but then (temporarily as it turns out) removed the threat once they agreed to address the flow of fentanyl into the U.S. However, this tactic is a dangerous game. For the threat of tariffs to work, the nations you are negotiating with must believe you are willing to impose the tariffs you are threatening. This can lead to a difficult decision wherein you either have to back down from your threat and lose reputation, or follow through and impose the tariffs even though you do not want to.
3. Protection of Infant Industries: It is possible that imposing tariffs on specific goods can foster the growth of developing industries that would not have been able to grow in the environment of foreign competition that existed without tariff protection. It is also possible that these protected industries could create more wealth for the nation once they are grown than would have been generated in the no-tariff scenario. Most economists argue that there is not much historical evidence of this occurring. Although the infant industry argument is possible, it relies on the assumption that the government can effectively identify which firms are going to prosper and bring greater economic benefits than would be accrued due to free trade. The government not only has to identify which infant industries to protect, but it also must have the appropriate incentives and mechanisms to carry out the protection. In reality, no one can consistently identify the appropriate infant industries to support.
4. Revenue: Tariffs can raise revenue for the government, but they are not capable of funding the current levels of government spending for many developed nations.

The “Chicken War” of the 1960s was a trade dispute between the United States and the European Economic Community (EEC), triggered by the EEC’s introduction of tariffs on imported chicken to protect its domestic poultry industry, leading to US retaliatory tariffs on trucks and other goods. Graphic courtesy of the Library of Congress.Cons

1. Economic Inefficiency: Let us imagine a scenario where person A and person B are trading with each other. The government then imposes a tax on the purchase of person B’s goods. Both person A and B are affected because person A must pay more for person B’s goods and person B cannot sell as many goods to person A. The same logic applies to tariffs. This is the process by which tariffs distort markets and lead to deadweight economic loss. Often, people assume that tariffs help the imposing country and hurt the country forced to pay them. This is incorrect. Tariffs hurt both countries, as both persons A and B are harmed due to the loss of economic efficiency. In addition, protectionist tariffs shelter domestic industries from competition, thereby allowing them to be less efficient. Lessened efficiency leads to poorer quality products and higher prices. Lastly, tariffs can disrupt supply chains that span multiple countries. For example, US tariffs on Chinese goods increased costs for American manufacturers that rely on parts imported from China.5 Disrupting supply chains also leads to economic inefficiency.
2. Higher Prices for Consumers: In our thought experiment above, person A must pay more for person B’s goods after the tariff is imposed. This is how tariffs raise prices for domestic consumers.
3. Trade Wars: Tariffs can spark trade wars that end up greatly decreasing the amount of trade across nations. When country A imposes tariffs on country B, country B may react by imposing counter-tariffs on country A. This causes an expanding cycle that leads to further decreases in trade and economic efficiency. A well-known example is the “Chicken War” in the 1960s, in which the U.S. imposed a 25% tariff on light trucks from Western Europe, which is still in place today.
4. Corruption: Once tariffs are enacted, they are politically difficult to remove. The costs of tariffs are thinly spread over millions of Americans, whereas the benefits are concentrated in a comparatively small number of people involved in specific industries. This makes the beneficiaries more politically motivated to maintain the tariffs than the general populace is to resist them, leading to long-lasting tariffs that aid a powerful few while harming the public.

Although tariffs have some theoretical benefits in specific situations, the competence and incentives of the U.S. political system often do not allow these benefits to come to fruition. Tariffs almost always come with the cost of economic inefficiency, which is why economists generally agree that tariffs do more harm than good. Does the increase in U.S. tariffs, particularly on China, since 2016 mark the end of the era of reciprocity or is it just a blip? The answer will affect the economic well-being of Americans and people around the world. 

The history of tariffs described in this article is largely based on Clashing Over Commerce by Douglas Irwin (2017).

The author would like to thank Professor John L. Turner at the University of Georgia for his invaluable input.

Throughout the early modern period—from the rise of the nation state through the nineteenth century—the predominant economic ideology of the Western world was mercantilism, or the belief that nations compete for a fixed amount of wealth in a zero-sum game: the +X gain of one nation means the –X loss of another nation, with the +X and –X summing to zero. The belief at the time was that in order for a nation to become wealthy, its government must run the economy from the top down through strict regulation of foreign and domestic trade, enforced monopolies, regulated trade guilds, subsidized colonies, accumulation of bullion and other precious metals, and countless other forms of economic intervention, all to the end of producing a “favorable balance of trade.” Favorable, that is, for one nation over another nation. As President Donald Trump often repeats, “they’re ripping us off!” That is classic mercantilism and economic nationalism speaking.

Adam Smith famously debunked mercantilism in his 1776 treatise An Inquiry into the Nature and Causes of the Wealth of Nations. Smith’s case against mercantilism is both moral and practical. It is moral, he argued, because: “To prohibit a great people…from making all that they can of every part of their own produce, or from employing their stock and industry in the way that they judge most advantageous to themselves, is a manifest violation of the most sacred rights of mankind.”1 It is practical, he showed, because: “Whenever the law has attempted to regulate the wages of workmen, it has always been rather to lower them than to raise them.”2

Producers and Consumers

Adam Smith’s The Wealth of Nations was one long argument against the mercantilist system of protectionism and special privilege that in the short run may benefit producers but which in the long run harms consumers and thereby decreases the wealth of a nation. All such mercantilist practices benefit the producers, monopolists, and their government agents, while the people of the nation—the true source of a nation’s wealth—remain impoverished: “The wealth of a country consists, not of its gold and silver only, but in its lands, houses, and consumable goods of all different kinds.” Yet, “in the mercantile system, the interest of the consumer is almost always constantly sacrificed to that of the producer.”3

Adam Smith statue in Edinburgh, Scotland. Photo by K. Mitch Hodge / Unsplash

The solution? Hands off. Laissez Faire. Lift trade barriers and other restrictions on people’s economic freedoms and allow them to exchange as they see fit for themselves, both morally and practically. In other words, an economy should be consumer driven, not producer driven. For example, under the mercantilist zero-sum philosophy, cheaper foreign goods benefit consumers but they hurt domestic producers, so the government should impose protective trade tariffs to maintain the favorable balance of trade.  

But who is being protected by a protective tariff? Smith showed that, in principle, the mercantilist system only benefits a handful of producers while the great majority of consumers are further impoverished because they have to pay a higher price for foreign goods. The growing of grapes in France, Smith noted, is much cheaper and more efficient than in the colder climes of his homeland, for example, where “by means of glasses, hotbeds, and hotwalls, very good grapes can be raised in Scotland” but at a price thirty times greater than in France. “Would it be a reasonable law to prohibit the importation of all foreign wines, merely to encourage the making of claret and burgundy in Scotland?” Smith answered the question by invoking a deeper principle: 

What is prudence in the conduct of every private family, can scarce be folly in that of a great kingdom. If a foreign country can supply us with a commodity cheaper than we ourselves can make it, better buy it of them.4

This is the central core of Smith’s economic theory: “Consumption is the sole end and purpose of all production; and the interest of the producer ought to be attended to, only so far as it may be necessary for promoting that of the consumer.” The problem is that the system of mercantilism “seems to consider production, and not consumption, as the ultimate end and object of all industry and commerce.”5 So what?

When production is the object, and not consumption, producers will appeal to top-down regulators instead of bottom-up consumers. Instead of consumers telling producers what they want to consume, government agents and politicians tell consumers what, how much, and at what price the products and services will be that they consume. This is done through a number of different forms of interventions into the marketplace. Domestically, we find examples in tax favors for businesses, tax subsidies for corporations, regulations (to control prices, imports, exports, production, distribution, and sales), and licensing (to control wages, protect jobs).6 Internationally, the interventions come primarily through taxes under varying names, including “duties,” “imposts,” “excises,” “tariffs,” “protective tariffs,” “import quotas,” “export quotas,” “most-favored nation agreements,” “bilateral agreements,” “multilateral agreements,” and the like. 

Such agreements are never between the consumers of two nations; they are between the politicians and the producers of the nations. Consumers have no say in the matter, with the exception of indirectly voting for the politicians who vote for or against such taxes and tariffs. And they all sum to the same effect: the replacement of free trade with “fair trade” (fair for producers, not consumers), which is another version of the mercantilist “favorable balance of trade” (favorable for producers, not consumers). Mercantilism is a zero-sum game in which producers win by the reduction or elimination of competition from foreign producers, while consumers lose by having fewer products from which to choose, along with higher prices and often lower quality products. The net result is a decrease in the wealth of a nation.

The principle is as true today as it was in Smith’s time, and we still hear the same objections Smith did: “Shouldn’t we protect our domestic producers from foreign competition?” And the answer is the same today as it was two centuries ago: no, because “consumption is the sole end and purpose of all production.”  

Nonzero Economics

The founders of the United States and the framers of the Constitution were heavily influenced by the Enlightenment thinkers of England and the continent, including and especially Adam Smith. Nevertheless, it was not long after the founding of the country before our politicians began to shift the focus of the economy from consumption to production. In 1787, the United States Constitution was ratified, which included Article 1, Section 8: “The Congress shall have the power to lay and collect taxes, duties, imposts, and excises to cover the debts of the United States.” As an amusing exercise in bureaucratic wordplay, consider the common usages of these terms in the Oxford English Dictionary. 

Tax: “a compulsory contribution to the support of government”
Duty: “a payment to the public revenue levied upon the import, export, manufacture, or sale of certain commodities”
Impost: “a tax, duty, imposition levied on merchandise”
Excise: “any toll or tax.” 

(Note the oxymoronic phrase “compulsory contribution” in the first definition.)

A revised Article 1, Section 8 reads: “The Congress shall have the power to lay and collect taxes, taxes, taxes, and taxes to cover the debts of the United States.”

A revised Article 1, Section 8 of the Constitution reads: “The Congress shall have the power to lay and collect taxes, taxes, taxes, and taxes to cover the debts of the United States.” Photo by Anthony Garand / Unsplash

In the U.K. and on the continent, mercantilists dug in while political economists, armed with the intellectual weapons provided by Adam Smith, fought back, wielding the pen instead of the sword. The nineteenth-century French economist Frédéric Bastiat, for example, was one of the first political economists after Smith to show what happens when the market depends too heavily on top-down tinkering from the government. In his wickedly raffish The Petition of the Candlemakers, Bastiat satirizes special interest groups—in this case candlemakers—who petition the government for special favors: 

We are suffering from the ruinous competition of a foreign rival who apparently works under conditions so far superior to our own for the production of light, that he is flooding the domestic market with it at an incredibly low price.... This rival... is none other than the sun.... We ask you to be so good as to pass a law requiring the closing of all windows, dormers, skylights, inside and outside shutters, curtains, casements, bull’s-eyes, deadlights and blinds; in short, all openings, holes, chinks, and fissures.7

Zero-sum mercantilist models hung on through the nineteenth and twentieth centuries, even in America. Since the income tax was not passed until 1913 through the Sixteenth Amendment, for most of the country’s first century the practitioners of trade and commerce were compelled to contribute to the government through various other taxes. Since foreign trade was not able to meet the growing debts of the United States, and in response to the growing size and power of the railroads and political pressure from farmers who felt powerless against them, in 1887 the government introduced the Interstate Commerce Commission. The ICC was charged with regulating the services of specified carriers engaged in transportation between states, beginning with railroads, but then expanded the category to include trucking companies, bus lines, freight carriers, water carriers, oil pipelines, transportation brokers, and other carriers of commerce.8 Regardless of its intentions, the ICC’s primary effect was interference with the freedom of people to buy and sell between the states of America.

The ICC was followed in 1890 with the Sherman Anti-Trust Act, which declared: “Every contract, combination in the form of trust or otherwise, or conspiracy, in restraint of trade or commerce among the several States, or with foreign nations, is declared to be illegal. Every person who shall make any contract or engage in any combination or conspiracy hereby declared to be illegal shall be deemed guilty of a felony,” resulting in a massive fine, jail, or both. 

When stripped of its obfuscatory language, the Sherman Anti-Trust Act and the precedent-setting cases that have been decided in the courts in the century since it was passed, allows the government to indict an individual or a company on one or more of four crimes: 

1.  Price gouging (charging more than the competition) 
2. Cutthroat competition (charging less than the competition)
3. Price collusion (charging the same as the competition), and 
4. Monopoly (having no competition).9, 10 

This was Katy-bar-the-door for anti-business legislators and their zero-sum mercantilist bureaucrats to restrict the freedom of consumers and producers to buy and sell, and they did with reckless abandon.  

Completing Smith’s Revolution

Tariffs are premised on a win-lose, zero-sum, producer-driven economy, which ineluctably leads to consumer loss. By contrast, a win-win, nonzero, consumer-driven economy leads to consumer gain. Ultimately, Smith held, a consumer-driven economy will produce greater overall wealth in a nation than will a producer-driven economy. Smith’s theory was revolutionary because it is counterintuitive. Our folk economic intuitions tell us that a complex system like an economy must have been designed from the top down, and thus it can only succeed with continual tinkering and control from the top. Smith amassed copious evidence to counter this myth—evidence that continues to accumulate two and a half centuries later—to show that, in the modern language of complexity theory, the economy is a bottom-up self-organized emergent property of complex adaptive systems. 

Adam Smith launched a revolution that has yet to be fully realized. A week does not go by without a politician, economist, or social commentator bemoaning the loss of American jobs, American manufacturing, and American products to foreign jobs, foreign manufacturing, and foreign products. Even conservatives—purportedly in favor of free markets, open competition, and less government intervention in the economy—have few qualms about employing protectionism when it comes to domestic producers, even at the cost of harming domestic consumers.

Citing the need to protect the national economic interest—and Harley-Davidson—Ronald Reagan raised tariffs on Japanese motorcycles from 4.4 percent to 49.4 percent. Photo by Library of Congress / Unsplash

Even the icon of free market capitalism, President Ronald Reagan, compromised his principles in 1982 to protect the Harley-Davidson Motor Company when it was struggling to compete against Japanese motorcycle manufactures that were producing higher quality bikes at lower prices. Honda, Kawasaki, Yamaha, and Suzuki were routinely undercutting Harley-Davidson by $1500 to $2000 a bike in comparable models.

On January 19, 1983, the International Trade Commission ruled that foreign motorcycle imports were a threat to domestic motorcycle manufacturers, and a 2-to-1 finding of injury was ruled on petition by Harley-Davidson, which complained that it could not compete with foreign motorcycle producers.10 On April 1, Reagan approved the ITC recommendation, explaining to Congress, “I have determined that import relief in this case is consistent with our national economic interest,” thereby raising the tariff from 4.4 percent to 49.4 percent for a year, a ten-fold tax increase on foreign motorcycles that was absorbed by American consumers. The protective tariff worked to help Harley-Davidson recover financially, but it was American motorcycle consumers who paid the price, not Japanese producers. As the ITC Chairman Alfred E. Eckes explained about his decision: “In the short run, price increases may have some adverse impact on consumers, but the domestic industry’s adjustment will have a positive long-term effect. The proposed relief will save domestic jobs and lead to increased domestic production of competitive motorcycles.”11

Photo by Lisanto 李奕良 / Unsplash

Whenever free trade agreements are proposed that would allow domestic manufacturers to produce their goods cheaper overseas and thereby sell them domestically at a much lower price than they could have with domestic labor, politicians and economists, often under pressure from trade unions and political constituents, routinely respond disapprovingly, arguing that we must protect our domestic workers. Recall Presidential candidate Ross Perot’s oft-quoted 1992 comment in response to the North American Free Trade Agreement (NAFTA) about the “giant sucking sound” of jobs being sent to Mexico from the United States.

In early 2007, the Nobel laureate economist Edward C. Prescott lamented that economists invest copious time and resources countering the myth that it is “the government’s economic responsibility to protect U.S. industry, employment and wealth against the forces of foreign competition.” That is not the government’s responsibility, says Prescott, echoing Smith, which is simply “to provide the opportunity for people to seek their livelihood on their own terms, in open international markets, with as little interference from government as possible.” Prescott shows that “those countries that open their borders to international competition are those countries with the highest per capita income” and that open economic borders “is the key to bringing developing nations up to the standard of living enjoyed by citizens of wealthier countries.”12

“Protectionism is seductive,” Prescott admits, “but countries that succumb to its allure will soon have their economic hearts broken. Conversely, countries that commit to competitive borders will ensure a brighter economic future for their citizens.” But why exactly do open economic borders, free trade, and international competition lead to greater wealth for a nation? Writing over two centuries after Adam Smith, Prescott reverberates the moral philosopher’s original insight:

It is openness that gives people the opportunity to use their entrepreneurial talents to create social surplus, rather than using those talents to protect what they already have. Social surplus begets growth, which begets social surplus, and so on. People in all countries are motivated to improve their condition, and all countries have their share of talented risk-takers, but without the promise that a competitive system brings, that motivation and those talents will only lie dormant.13

The Evolutionary Origins of Tariffs and Zero-Sum Economics

Why is mercantilist zero-sum protectionism so pervasive and persistent? Bottom-up invisible hand explanations for complex systems are counterintuitive because of our folk economic propensity to perceive designed systems to be the product of a top-down designer. But there is a deeper reason grounded in our evolved social psychology of group loyalty. The ultimate reason that Smith’s revolution has not been fulfilled is that we evolved a propensity for in-group amity and between-group enmity, and thus it is perfectly natural to circle the wagons and protect one’s own, whoever or whatever may be the proxy for that group. Make America Great Again! 

For the first 90,000 years of our existence as a species we lived in small bands of tens to hundreds of people. In the last 10,000 years some bands evolved into tribes of thousands, some tribes developed into chiefdoms of tens of thousands, some chiefdoms coalesced into states of hundreds of thousands, and a handful of states conjoined together into empires of millions. The attendant leap in food-production and population that accompanied the shift to chiefdoms and states allowed for a division of labor to develop in both economic and social spheres. Full-time artisans, craftsmen, and scribes worked within a social structure organized and run by full-time politicians, bureaucrats, and, to pay for it all, tax collectors. The modern state economy was born.

In this historical trajectory our group psychology evolved and along with it a propensity for xenophobia—in-group good, out-group bad. In the Paleolithic social environment in which our moral commitments evolved, one’s fellow in-group members consisted of family, extended family, friends, and community members who were well known to each other. To help others was to help oneself. Those groups who practiced in-group harmony and between-group antagonism would have had a survival advantage over those groups who experienced within-group social divide and decoherence, or haphazardly embraced strangers from other groups without first establishing trust. Because our deep social commitments evolved as part of our behavioral repertoire of responses for survival in a complex social environment, we carry the seeds of such in-group inclusiveness today. The resulting within-group cohesiveness and harmony carries with it a concomitant tendency for between-group xenophobia and tribalism that, in the context of a modern economic system, leads to protectionism and mercantilism.

And tariffs. We must resist the tribal temptation.

I think it’s increasingly difficult to argue that the recent boom in artificial intelligence (AI) is mostly hype. There is a lot of hype, but don’t let that distract you from the real progress. The best indication of this is applications in scientific research, because the outcomes are measurable and objective. AI applications are particularly adept at finding patterns in vast sets of data, finding patterns in hours that might have required months of traditional research. We recently discussed on the SGU using AI to sequence proteins, which is the direction that researchers are going in. Compared to the traditional method using AI analysis is faster and better at identifying novel proteins (not already in the database).

One SGU listener asked an interesting question after our discussion of AI and protein sequencing that I wanted to explore – can we apply the same approach to DNA and can this result in reverse-engineering the genetic sequence from the desired traits? AI is already transforming genetic research. AI apps allow for faster, cheaper, and more accurate DNA sequencing, while also allowing for the identification of gene variants that correlate with a disease or a trait. Genetics is in the sweet spot for these AI applications – using large databases to find meaningful patterns. How far will this tech go, and how quickly.

We have already sequenced the DNA of over 3,000 species. This number is increasing quickly, accelerated by AI sequencing techniques. We also have a lot of data about gene sequences and the resulting proteins, non-coding regulatory DNA, gene variants and disease states, and developmental biology. If we trained an AI on all this data, could it then make predictions about the effects of novel gene variants? Could it also go from a desired morphological trait back to the genetic sequence that would produce that trait? Again, this sounds like the perfect application for AI.

In the short run this approach is likely to accelerate genetic research and allow us to ask questions that would have been impractical otherwise. This will build the genetic database itself. In the not-so-medium term this could also become a powerful tool of genetic modification. We won’t necessarily need to take a gene from one species and put it into another. We could simply predict which changes would need to be made to the existing genes of a cultivar to get the desired trait. Then we can use CRISPR (or some other tool) to make those specific changes to the genome.

How far will this technology go? At some point in the long term could we, for example, ask an AI to start with a chicken genome and then predict which specific genetic changes would be necessary to change that chicken into a velociraptor? We could change an elephant into a wooly mammoth. Could this become a realistic tool of deextinction? Could we reduce the risk of extinction in an endangered species by artificially increasing the genetic diversity in the remaining population?

What I am describing so far is actually the low-hanging-fruit. AI is already accelerating genetics research. It is already being used for genetic engineering, to help predict the net effects of genetic changes to reduce the chance of unintended consequences. This is just one step away from using AI to plan the changes in the first place. Using AI to help increase genetic diversity in at-risk populations and for deextinction is a logical next step.

But that is not where this thought experiment ends. Of course whenever we consider making genetic changes to humans the ethics becomes very complicated. Using AI and genetic technology for designer humans is something we will have to confront at some point. What about entirely artificial organisms? At what point can we not only tweak or even significantly transform existing species, but design a new species from the ground up? The ethics of this are extremely complicated, as are the potential positive and negative implications. The obvious risk would be releasing into the wild a species that would be the ultimate invasive species.

There are safeguards that could be created. All such creatures, for example, could be not just sterile but completely unable to reproduce. I know – this didn’t work out well on Jurassic Park, nature finds a way, etc, but there are potential safeguards so complete that no mutation would fix, such as completely lacking reproductive organs or gametes. There is also the “lysine contingency” – essentially some biological factor that would prevent the organism from surviving for long outside a controlled environment.

This all sound scary, but at some point we could theoretically get to acceptable safety levels. For example, imagine a designer pet, with a suite of desirable features. This creature cannot reproduce, and if you don’t regularly feed it special food it will die, or perhaps just go into a coma from which it can be revived. Such pets might be safer than playing genetic roulette with random breeding of domesticated predators. This goes not just for pets but for a variety of work animals.

Sure – PETA will have a meltdown. There are legitimate ethical considerations. But I don’t think they are unresolvable.

In any case, we are rapidly hurtling toward this future. We should at least head into this future with our eyes open.

The post Will AI Bring Us Jurassic Park first appeared on NeuroLogica Blog.

A framework inspired by evolution may demonstrate why two observers see the same non-quantum world emerge from the many fuzzy probabilities of the quantum realm

I've long said that the antivax movement is borderline eugenicist (or at least social Darwinist) in nature. Now that a second child has died of measles, it's time for me to take a look at the "soft eugenics" of the antivax movement.

The post Measles, MAHA, and “soft eugenics” first appeared on Science-Based Medicine.

In 1986, the Voyager 2 spacecraft made a flyby of Uranus. It gave us the first detailed images of the distant world. What was once only seen as a featureless pale blue orb was revealed to be...well, a mostly featureless pale blue orb. The flyby gave astronomers plenty of data, but the images Voyager 2 returned were uninspiring. That's because Voyager only viewed Uranus for a moment in time. Things change slowly on the ice giant world, and to study them you need to take a longer view.

Mars exploration technology has seen a lot of recent successes. MOXIE successfully made oxygen from the atmosphere, while Ingenuity soared above the red planet 72 times. However, to date, no one has ever achieved one thing that will be absolutely critical to any long-term presence on Mars - making drinkable water. There have been plenty of ideas on how to do that. Still, NASA recently started funding a Worcester Polytechnic Institute (WPI) graduate student named Lydia Ellen Tonani-Penha to look into the problem under their Space Technology Graduate Research Opportunities (NSTGRO) funding program. Her Project Tethys will examine ways to purify the frozen or liquid brine that Mars is infused with.

NASA's Perseverance was scanning the rim of Jezero Crater when it spotted a Martian dust devil overtake and consume another smaller one. The rover was about a kilometer away from the larger dust devil, which was about 65 meters wide. The smaller one was about 5 meters wide. This isn't Perseverance's first encounter with dust devils. It's seen clusters dancing around it and even captured audio of a dust devil on Mars for the first time.