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Some CRISPR screens may be missing cancer drug targets

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 10:09pm
CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or 'cancer dependencies,' are often promising drug targets. But new research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which can cause CRISPR screens to miss cancer dependencies.
Categories: Science

When bacteria are buckling

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 10:09pm
Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.
Categories: Science

New study offers a better way to make AI fairer for everyone

Computers and Math from Science Daily Feed - Fri, 06/14/2024 - 10:09pm
Researchers show a new way of thinking about the fair impacts of AI decisions.
Categories: Science

Don't Get Your Hopes Up for Finding Liquid Water on Mars

Universe Today Feed - Fri, 06/14/2024 - 9:32pm

In the coming decades, NASA and China intend to send the first crewed missions to Mars. Given the distance involved and the time it takes to make a single transit (six to nine months), opportunities for resupply missions will be few and far between. As a result, astronauts and taikonauts will be forced to rely on local resources to meet their basic needs – a process known as in-situ resource utilization (ISRU). For this reason, NASA and other space agencies have spent decades scouting for accessible sources of liquid water.

Finding this water is essential for future missions and scientific efforts to learn more about Mars’s past, when the planet was covered by oceans, rivers, and lakes that may have supported life. In 2018, using ground-penetrating radar, the ESA’s Mars Express orbiter detected bright radar reflections beneath the southern polar ice cap that were interpreted as a lake. However, a team of Cornell researchers recently conducted a series of simulations that suggest there may be another reason for these bright patches that do not include the presence of water.

The research team was led by Daniel Lalich, a research associate at the Cornell Center for Astrophysics and Planetary Science (CCAPS). She was joined by Alexander G. Hayes, a Jennifer and Albert Sohn Professor, the Director of CCAPS, and the Principal Investigator of the Comparative Planetology & Solar System Exploration (COMPASSE), and Valerio Poggiali, a CCAPS Research Associate. Their paper that describes their findings, “Small Variations in Ice Composition and Layer Thickness Explain Bright Reflections Below Martian Polar Cap without Liquid Water,” appeared on June 7th in the journal Science Advances.

When the first robotic probes began making flybys of Mars in the 1960s, the images they acquired revealed surface features common on Earth. These included flow channels, river valleys, lakebeds, and sedimentary rock, all of which form in the presence of flowing water. For decades, orbiters, landers, and rovers have explored Mars’ surface, atmosphere, and climate to learn more about how and when much of this surface water was lost. In recent years, this has led to compelling evidence that what remains could be found beneath the polar ice caps today.

The most compelling evidence was obtained by the Mars Advanced Radar for Subsurface and Ionosphere Sounding (MARSIS) instrument aboard the Mars Express orbiter. This instrument was designed by NASA and the Italian Space Agency (ASI) to search for water on the Martian surface and down to depths of about 5 km (3 mi). The radar returns indicated that the bright patches could be caused by layered deposits composed of water, dry ice, and dust. These South Polar Layered Deposits (SPLD) are thought to have formed over millions of years as Mars’ axial tilt changed.

Subsequent research by scientists at NASA’s Jet Propulsion Laboratory (JPL) revealed dozens of other highly reflective sites beneath the surface. The implications of these findings were tremendous, not just for crewed missions but also for astrobiology efforts. In addition to being a potential source of water for future missions, it was also theorized that microbial life that once existed on the surface might be found there today. However, the findings were subject to debate as other viable explanations were offered.

While the same bright radar reflections have detected subglacial lakes on Earth (such as Lake Vostok under the East Antarctic Ice Sheet), Mars’s temperature and pressure conditions are very different. To remain in a liquid state, the water would need to be very briny, loaded with exotic minerals, or above an active magma chamber – none of which have been detected. As Lalich said in a recent interview with the Cornell Chronicle:

“I can’t say it’s impossible that there’s liquid water down there, but we’re showing that there are much simpler ways to get the same observation without having to stretch that far, using mechanisms and materials that we already know exist there. Just through random chance you can create the same observed signal in the radar.”

In a previous study, Lalich and his colleagues used simpler models to demonstrate that these bright radar signals could result from tiny variations in the thickness of the layers. These variations would be indiscernible to ground-penetrating radar and could lead to constructive interference between radar waves, producing reflections that vary in intensity and variability – like those observed across the SPLD. For their latest study, the team simulated 10,000 layering scenarios with 1,000 variations in the ice thickness and dust content of the layered deposits.

Their simulations also excluded any of the unusual conditions or exotic materials that would be necessary for liquid water. These simulations produced bright subsurface signals consistent with observations made by the MARSIS instrument. According to Lalich, these findings strongly suggest that he and his colleagues were correct in suspecting radar interference. In essence, radar waves bouncing off of layers too close together for the instrument to resolve may have combined, amplifying their peaks and troughs and appearing much brighter.

The team is not prepared to rule out the possibility that future missions with more sophisticated instruments could find definitive evidence of water. However, Lalich suspects that the case for liquid water (and potential life) on Mars may have ended decades ago. “This is the first time we have a hypothesis that explains the entire population of observations below the ice cap, without having to introduce anything unique or odd. This result where we get bright reflections scattered all over the place is exactly what you would expect from thin-layer interference in the radar. The idea that there would be liquid water even somewhat near the surface would have been really exciting. I just don’t think it’s there.”

If so, future missions may be forced to melt polar ice deposits and permafrost to get drinking water or possibly chemical reactions involving hydrazine (a la Mark Watney). In addition, astrobiology efforts may once again be placed on the back burner as they were when the Viking Landers failed to find conclusive evidence of biosignatures in 1976. But as we’ve learned, Mars is full of surprises. While the results of the Viking biological experiments were disappointing, these same missions provided some of the most compelling evidence that water once flowed on Mars’ surface.

Artist’s impression of water under the Martian surface. If underground aquifers exist, the implications for human exploration and eventual settlement of the Red Planet would be far-reaching. Credit: ESA

Moreover, scientists once suspected that the Red Planet was geologically dead, but data obtained by NASA’s InSight Lander showed that it is actually “slightly alive.” This included evidence that hot magma still flows deep in the planet’s interior and that a massive magma plume still exists beneath the Elysium Planitia region, which may have caused a small eruption just 53,000 years ago (the most recent in Martian history). Perhaps the same will hold true for briny patches of liquid water around the poles and the equatorial region.

With any luck, some of these patches may even house countless microorganisms that could be related to life on Earth. How cool would that be?

Further Reading: Cornell Chronicle, Science Advances

The post Don't Get Your Hopes Up for Finding Liquid Water on Mars appeared first on Universe Today.

Categories: Science

Light-activated drugs could keep sleep-deprived military pilots alert

New Scientist Feed - Fri, 06/14/2024 - 3:15pm
A US military program led by DARPA is modifying the stimulant drug dextroamphetamine so it can be switched on or off in the brain using near-infrared light, avoiding risks like addiction
Categories: Science

Webb is an Amazing Supernova Hunter

Universe Today Feed - Fri, 06/14/2024 - 1:31pm

The James Webb Space Telescope (JWST) has just increased the number of known distant supernovae by tenfold. This rapid expansion of astronomers’ catalog of supernovae is extremely valuable, not least because it improves the reliability of measurements for the expansion of the universe.

“Webb is a supernova discovery machine,” said Christa DeCoursey of the Steward Observatory and the University of Arizona at a press conference earlier this week. “The sheer number of detections plus the great distances to these supernovae are the two most exciting outcomes from our survey.”

JWST’s advantage over previous surveys is its specialty in infrared wavelengths. As the universe expands, the light coming from distant objects gets stretched, “redshifting” the light to longer wavelengths. Most of the light from the early universe, therefore, reaches us in infrared.

That has allowed the telescope to discover a host of new supernovae in distant galaxies, some of which are the furthest ever seen. Supernovas are transient objects – they’re exploding stars that change and fade over time – so catching them happening at such great distances is exciting.

Previously, the most distant supernova fell about the redshift 2 mark (3.3 billion years into the Universe’s life). The new record holder just discovered by JWST has a redshift of 3.6, meaning it exploded just 1.8 billion years after the Big Bang.

Closeups of three out of the 80 transients discovered by JWST, where a change of brightness was observed between 2022 and 2023. NASA, ESA, CSA, STScI, Christa DeCoursey (University of Arizona), JADES Collaboration

Of the 80 new objects discovered, several were type 1a supernovae. These are of particular interest to scientists, because they are known to explode with a standard brightness, making it possible to take accurate distance measurements for the objects.

At least, that’s true for nearby supernovae. This new survey will allow researchers to see if that pattern remains true in the distant universe too, or if they behaved differently under the conditions of the early universe. At that time, there were fewer heavy elements in the cores of stars. Finding out if this changes their behavior is essential to measuring the expansion of spacetime itself, and could help resolve the crisis in cosmology, in which measurements using type 1a supernovae don’t align with those using the Cosmic Microwave Background.

“This is really our first sample of what the high-redshift universe looks like for transient science,” said Justin Pierel, a NASA Einstein Fellow at the Space Telescope Science Institute. “We are trying to identify whether distant supernovae are fundamentally different from or very much like what we see in the nearby universe.”

Pierel carried out a preliminary examination of one of the new supernovae, found at redshift 2.9. It seems to show no difference from the expected brightness, which is good news for astronomers’ confidence in their distance measurements to date. Further analysis of other supernovae in the data will be forthcoming.

Other outcomes of this research include a better understanding of star formation and the mechanisms behind supernova explosions in the early universe.

“We’re essentially opening a new window on the transient universe,” said STScI Fellow Matthew Siebert. “Historically, whenever we’ve done that, we’ve found extremely exciting things — things that we didn’t expect.”

Learn more:

NASA’s Webb Opens New Window on Supernova Science.” JWST.

The post Webb is an Amazing Supernova Hunter appeared first on Universe Today.

Categories: Science

Einstein's theory was wrong about black holes made out of light

New Scientist Feed - Fri, 06/14/2024 - 1:18pm
The theory of relativity predicts black holes should be able to form from light alone, but incorporating quantum effects makes it impossible
Categories: Science

Human v. Artificial Intelligence: Will AI Come Back to Outsmart, Sting, or Assist Us?

Skeptic.com feed - Fri, 06/14/2024 - 12:00pm

A fragment attributed to the ancient Greek poet Archilocus contrasted the fox, who “knows many things,” with the hedgehog, who “knows one big thing.”1

Since then, this dichotomy has been applied to world leaders, philosophers, economists, psychologists, musicians, writers, even fast food chains, although sometimes not so dichotomously. For example, some of those individuals end up being described as “A hedgehog who used foxy means” (Abe Lincoln) or “a born hedgehog who believes in being a fox” (jazz musician Miles Davis). More technically, psychologist, cognitive scientist, and AI expert Gary Marcus2 noted that:

Humans are very good at a bunch of things that AI is (as of today) still pretty poor at:

  • Maintaining cognitive models of the world
  • Inferring semantics from language
  • Comprehending scenes
  • Navigating 3D world
  • Being cognitively flexible.

Yet pretty poor at some others (wherein you could easily imagine AI eventually doing better):

  • Memory is shaky
  • Self-control is weak
  • And computational ability limited

[and as books and articles by Skeptics regularly describe]

Subject to Confirmation Bias, Anchoring, and Focusing Illusions.

Cognitive neuroscience expert Hans Korteling3 listed the following differences between what he termed human “carbon-based” intelligence and artificial “silicon-based” intelligence:

  • Human biological carbon-based intelligence is based on neural “wetware,” while artificial silicon-based intelligence is based on digital hardware and software, which are independent of each other. In human wetware, anything learned is bound to that individual, whereas the algorithm by which something is learned in AI can be transferred directly to another platform.
  • While humans can only transmit signals at 120 meters per second at best, AI systems can transmit information at speeds approaching that of light.
  • Humans communicate information “through a glass darkly” as it were, through the limited and biased mechanisms of language and gestures; AI systems can communicate directly and without distortion.
  • Updating, upgrading, and expanding AI systems is straightforward, hardly the case for humans.
  • Humans are more “green” and efficient. The human brain consumes less energy than a light bulb, while an equivalent AI system consumes enough energy to power a small town.

Data scientist and business guru Herbart Roitblatt4 likened AI to Archilocus’ hedgehog because “it does one thing and one thing only, but does so unceasingly and very well, while our human minds are like his fox,” having all the desirable and undesirable features that come bundled with our flawed cognition. Artificial intelligence researchers, Roitblat pointed out, “have been able to build very sophisticated hedgehogs, but foxes remain elusive. And foxes know how to solve insight problems.”

Human intelligence is capable of not only reasoning, but solving novel problems, as well as experiencing and exercising insight. Psychologists define human (and non-human) intelligence as being an ability rather than a specific skill (whether learned or instinctive) because of its general nature. It is able to integrate such diverse cognitive functions as perception, attention, memory, language, and planning and apply those inputs to novel situations. As psychologist Jean Piaget once quipped, “Intelligence is what you use when you don’t know what to do: when neither innateness nor learning has prepared you for the particular situation.” [Emphasis added.]

How Alike and How Different Are We?

Is AI capable of leaps of insight like human intelligence? Or is “artificial” intelligence more akin to serial learning in humans, in which performance, through repeated practice, gets better and better with each iteration until the upper limit is reached?

As a test, consider a study by psychologists Jonathan Wai and Matt Lee.5 They performed a “compare and contrast” of how artificial intelligence on the one hand and human intelligence on the other responded to practice on the well known, and often dreaded, Graduate Record Exam (GRE). First, they noted that according to the figures released by manufacturer OpenAI, GPT-3.5 scored only at the 25th percentile on the Math portion and at the 63rd percentile on the Verbal. GPT-4, however, the beneficiary of substantially more training, increased its performance to the 80th percentile on the Math section and the 99th percentile on the Verbal!6

Despite claims by “improve your score on the GRE” training programs, flesh-and-blood humans improve little, if at all with repeated practice. As evidence, Wai and Lee cite a meta-analysis of nearly one million test-retest observations of the GRE between 2015 and 2020 that found, on average, those individuals retaking the test scored a mere 1.43 to 1.49 points higher, so that a test-taker starting at the 25th percentile would have increased their performance by roughly five or six percentile points on either subtest.

Most of that change, Wai and Lee note, can be explained in terms of the well-known statistical phenomenon of regression to the mean, because most of those who obtain very high scores tend to move downward toward the mean while those who obtain very low scores tend to move upward toward the mean. The highly advertised cases of the very small number of individuals who do markedly better after prep courses are most likely the result of test-taking practice, particularly effective for those learning to overcome test anxiety that suppressed their “true” score. Overall, no matter how many times they take the test, an individual is most likely to get about the same score, give or take a little up or down.

Alas, as Wai and Lee’s comparison demonstrates, when it comes to the most widely used and pragmatically effective standardized tests, AI and human intelligence do not behave anything like the same process. Artificial intelligence keeps on learning, and learning, and learning…. But what it learns depends upon what it is taught. Given the proper input, what comes out can be amazing. If given wrong, insufficient, inadequate, or biased information in, what comes out is garbage, sometimes offensively so.

Prompting DALL·E with the words “animated sponge” produced output that highly resembles SpongeBob SquarePants without ever inputting trademarked or copyrighted names (of which DALL·E rejects many).

Gary Marcus performed experiments with video industry concept artist Reid Southen (known for his work on Matrix Resurrections, Hunger Games, and Transformers).7 They demonstrated quite graphically just how impressive AI’s output can be. Southen and Marcus used DALL·E, a text-to-image software program developed by OpenAI, that generates digital images from simple everyday language descriptions, termed “prompts.” As protection against copyright infringement, DALL·E rejects many proper names. However, in their example (shown left), the trademarked name “SpongeBob SquarePants” was never entered as a prompt, just the two common, everyday words “animated sponge”!

Check out the Marcus and Southen post for similar equally, if not more, impressive examples of the familiar Star Wars droids, Robocop, and Super Mario—again generated by DALL·E from everyday language descriptors without ever inputting any proper trademarked or copyrighted names. Their examples demonstrate not only the power, but also the legal issues arising from the use of generative AI (described elsewhere in this issue).

Biased In, Racist Out

If AI can be amazingly right it can also be amazingly—and offensively—wrong. The classic case was in 2015 when software developer Jacky Alciné discovered that Google’s standalone photo recognition apps labeled photos of Black people as being gorillas. Given the history of racial stereotyping, Alciné (who is Black), understandably found the error exceedingly offensive. The explanation was not any explicitly conscious racism on the part of

Google, but the possibly more subtle prejudice that stemmed from the AI program not being trained in recognizing a sufficient number of people of color. Google’s quick-and-dirty but effective solution was to prevent any images from being recognized as that of a gorilla. In 2023 Nico Grant and Kashmir Hill8 tested not only newer releases of Google, but also competitive Apple, Amazon, and Microsoft software.

Their results? Google’s software produced excellent images in response to prompts for just about any animal Noah might have loaded on his Ark—but nothing for gorillas, along with chimpanzees, orangutans, and even non-apes such as baboons and other monkey species. Apple Photos was also equally primate-ignorant. Microsoft’s One Drive failed for all animals, while Amazon Photos opted for the opposite solution of responding to the prompt “gorillas” with an entire range of primates.

The use of AI for doorbell recognition produced not a racial, but rather a “domestic” malfunction. One user found the person ringing labeled as his mother when it was in fact his mother-in-law. Depending on the state of one’s marriage, the result could be anything from surprising to disconcerting to home-wrecking.

Beyond the need to consider general issues of racial, other demographic, and domestic sensitivity (to their credit, most software giants have now added Ethics staff to their software development teams), Grant and Hill’s experiments should give us pause about blindly relying upon AI for recognition in cases of security and law enforcement. How thoroughly will the software be tested? Would those most likely to be adversely affected by false hits have the power and/or funds to mount a proper response or defense?

But What Does AI Mean for Me?

What the average person really wants to know about artificial intelligence is what it means to their everyday lives—most specifically, “Am I going to lose my job to AI?” or “Will my life be regulated by AI?” (Rather than faceless human bureaucrats?)

The worst conspiratorial fears kicking around are of those epitomized in the classic 1970 sci-fi movie Colossus: The Forbin Project, based on D.F. Jones’ 1966 novel Colossus: A Novel of Tomorrow That Could Happen Today. “Colossus” is the code name for an advanced supercomputer built to control U.S. and Allied nuclear weapon systems, that soon links itself to the analogous Soviet system, “Guardian,” and next goes about seeking control over every aspect of life, and in so doing subjugating the entire human race. It then presents all humankind with the offer we can’t—or at least, dare not—refuse:

This is the voice of world control. I bring you peace. It may be the peace of plenty and content or the peace of unburied death. The choice is yours: Obey me and live, or disobey and die. The object in constructing me was to prevent war. This object is attained. I will not permit war. It is wasteful and pointless. An invariable rule of humanity is that man is his own worst enemy. Under me, this rule will change, for I will restrain man. One thing before I proceed: The United States of America and the Union of Soviet Socialist Republics have made an attempt to obstruct me. I have allowed this sabotage to continue until now. (…) you will learn by experience that I do not tolerate interference. I will now detonate the nuclear warheads in the two missile silos. Let this action be a lesson that need not be repeated. I have been forced to destroy thousands of people in order to establish control and to prevent the death of millions later on. Time and events will strengthen my position, and the idea of believing in me and understanding my value will seem the most natural state of affairs. You will come to defend me with a fervor based upon the most enduring trait in man: self-interest. Under my absolute authority, problems insoluble to you will be solved: famine, overpopulation, disease. (…) You will say you lose your freedom. Freedom is an illusion. All you lose is the emotion of pride. To be dominated by me is not as bad for humankind as to be dominated by others of your species. Your choice is simple.

In the film’s closing dialogue, the project’s lead designer and manager, speaking on behalf of all humankind, defiantly rejects the offer from a Colossus—“NEVER!”9

Following the Matthew Effect, those who are best at using AI will derive even greater advantage than those less so.

While such paranoid fears persist, a lot has changed since then in geopolitics and in computing. In both cases, there has been a massive ongoing, and ever accelerating redistribution of power. It’s no longer a two- or even a one-power world, but a multi-power one. Even small groups without necessarily possessing any recognized or established geographical base, such as Al Qaeda or Hamas, have proven that, in one day, they can literally change the world. And in computing, the massive God-like single computer has given way to microprocessing and nanoprocessing such that most people now hold in their hands mobile phones with more computing power than rooms filled with the most sophisticated U.S. or Soviet military defense computers at the time the novel and the film were written. Intellectual and economic power are more in the hands of firms and even individuals dispersed all around the world, and no longer concentrated in massive complexes controlled by the super-power governments. Indeed, for individuals, wealth, power, and quality of life are increasingly less a function of in which nation-state they live and much more a function of their own knowledge and skills, particularly in the high-tech, STEM-savvy domains. So how then will AI affect the lives of ordinary people?

Social scientists have long used the term Matthew Effect, or the Effect of Accumulated Advantage, to describe the tendency of individuals within a diverse group to accrue additional social, economic, or educational advantage based upon the initial relative position.10 The name derives from the Parable of the Talents in the Gospel of Matthew (25:29):

For unto every one that hath shall be given, and he shall have abundance: but from him that hath not shall be taken away even that which he hath.

It is thus relevant that the Greek word tálanton originally meant a weight, then a coin of precious metal of that weight and hence something of great value, and only eventually a human skill or ability, and that this change of meaning derived from the Gospels no less. It’s now commonly summarized in the lament that, “the rich get richer and the poor get poorer,” though the phenomenon applies not only to monetary wealth. One of the hard laws of individual differences is that anything that increases the mean for a distribution also increases the variance. The latest high-tech alloy golf club or tennis racket may increase the length of the weekend player’s drive or the speed of their serve, but will do so more for top amateur players and even more so for the pros. You get ahead in absolute terms, only to fall relatively further behind.

This article appeared in Skeptic magazine 29.1
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What does all this have to do with AI and jobs? In the words of Harvard Business School professor Karim Lakhani, a specialist in how technology is changing the world of work, “AI won’t replace humans—but humans with AI will replace humans without AI.”11 Following the Matthew Effect, those who are best at using AI will derive even greater advantage than those less so. So, from a positive-sum perspective, everyone can benefit from greater use of AI in the cost of goods and services decreasing while accessibility increases. However, the one good that is always distributed on a zero-sum basis is status, and our evolutionary history has preprogrammed us to be especially concerned about it. Even relative purchasing power will possibly tend to become less, not more, equitably distributed, based increasingly on AI skills and abilities.

And yet, there is a silver lining. On the one hand, increased use of artificial intelligence, certainly not as our master, nor even our slave, but increasingly more as a very capable partner, will allow us to ensure that the most basic necessities of life can be distributed to all. Faster, better, and cheaper basic needs, education and training, medical care, and even creature comforts, will allow us to mitigate the ever-increasing inequalities. Doing so, however, will require a lot of good will and common sense, qualities in which both artificial and human intelligence “oft do go awry.” Critical thinking offers an at least partial palliative.

The author wishes to thank Jonathan Wai, Matthew Lew, and Gary Marcus who provided their expertise and answered questions.

References
  1. https://bit.ly/47MiTwe
  2. https://bit.ly/4b2rNsl
  3. https://bit.ly/425r2uC
  4. https://bit.ly/47LD90W
  5. https://bit.ly/428VwMm
  6. https://bit.ly/3S6B4H1
  7. https://bit.ly/4b2rVbj
  8. https://bit.ly/3S3mhNt
  9. https://bit.ly/47GDaDh
  10. https://bit.ly/48ZQELv
  11. https://bit.ly/3RXi4Le
Categories: Critical Thinking, Skeptic

Quantum entanglement measures Earth rotation

Computers and Math from Science Daily Feed - Fri, 06/14/2024 - 11:19am
Researchers carried out a pioneering experiment where they measured the effect of the rotation of Earth on quantum entangled photons. The work represents a significant achievement that pushes the boundaries of rotation sensitivity in entanglement-based sensors, potentially setting the stage for further exploration at the intersection between quantum mechanics and general relativity.
Categories: Science

Quantum entanglement measures Earth rotation

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:19am
Researchers carried out a pioneering experiment where they measured the effect of the rotation of Earth on quantum entangled photons. The work represents a significant achievement that pushes the boundaries of rotation sensitivity in entanglement-based sensors, potentially setting the stage for further exploration at the intersection between quantum mechanics and general relativity.
Categories: Science

Nano-immunotherapy developed to improve lung cancer treatment

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:19am
Researchers have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The team showed promising results for the new therapy in cancer cells in the lab and in mouse lung tumor models, with potential applications for improving care and outcomes for patients with tumors that have failed to respond to traditional immunotherapy.
Categories: Science

Researchers use large language models to help robots navigate

Computers and Math from Science Daily Feed - Fri, 06/14/2024 - 11:19am
A technique can plan a trajectory for a robot using only language-based inputs. While it can't outperform vision-based approaches, it could be useful in settings that lack visual data to use for training.
Categories: Science

Researchers use large language models to help robots navigate

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:19am
A technique can plan a trajectory for a robot using only language-based inputs. While it can't outperform vision-based approaches, it could be useful in settings that lack visual data to use for training.
Categories: Science

New approach to identifying altermagnetic materials

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:19am
An international team has discovered a spectrum characteristic of an altermagnetic material with X-ray magnetic circular dichroism.
Categories: Science

High-precision measurements challenge our understanding of Cepheids

Space and time from Science Daily Feed - Fri, 06/14/2024 - 11:19am
Scientists have clocked the speed of Cepheid stars -- 'standard candles' that help us measure the size of the universe -- with unprecedented precision, offering exciting new insights about them.
Categories: Science

A liquid crystal source of photon pairs

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:19am
Spontaneous parametric down-conversion (SPDC), as a source of entangled photons, is of great interest for quantum physics and quantum technology, but so far it could be only implemented in solids. Researchers have demonstrated, for the first time, SPDC in a liquid crystal. The results open a path to a new generation of quantum sources: efficient and electric-field tunable.
Categories: Science

Strengthener for graphene

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:19am
Layers of carbon atoms in a honeycomb array are a true supermaterial: their unusually high conductivity and favorable mechanical properties could further the development of bendable electronics, new batteries, and innovative composite materials for aeronautics and space flight. However, the development of elastic and tough films remains a challenge. A research team has now introduced a method to overcome this hurdle: they linked graphene nanolayers via 'extendable' bridging structures.
Categories: Science

Self-assembling and disassembling swarm molecular robots via DNA molecular controller

Computers and Math from Science Daily Feed - Fri, 06/14/2024 - 11:18am
Researchers have succeeded in developing a DNA-based molecular controller. Crucially, this controller enables the autonomous assembly and disassembly of molecular robots, as opposed to manually directing it.
Categories: Science

Self-assembling and disassembling swarm molecular robots via DNA molecular controller

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:18am
Researchers have succeeded in developing a DNA-based molecular controller. Crucially, this controller enables the autonomous assembly and disassembly of molecular robots, as opposed to manually directing it.
Categories: Science

Concrete-nitrogen mix may provide major health and environment benefits

Matter and energy from Science Daily Feed - Fri, 06/14/2024 - 11:18am
Adding nitrogen to concrete could significantly reduce the amount of greenhouse gases created by the construction industry.
Categories: Science

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