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Physical signals as fate deciders: How mechanical forces extrude cells from tissues

Matter and energy from Science Daily Feed - Thu, 01/09/2025 - 9:56am
Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is achieved by cell extrusion programs, a checkpoint mechanism eliminating unwanted or harmful cells. Researchers have now demonstrated how physical signals can have an impact on the fate of extruding cells governing their death or survival. The results may establish novel paths for understanding tissue properties in both normal and pathological conditions.
Categories: Science

New AI model TabPFN enables faster and more accurate predictions on small tabular data sets

Matter and energy from Science Daily Feed - Thu, 01/09/2025 - 9:56am
A team has developed a new method that facilitates and improves predictions of tabular data, especially for small data sets with fewer than 10,000 data points. The new AI model TabPFN is trained on synthetically generated data before it is used and thus learns to evaluate possible causal relationships and use them for predictions.
Categories: Science

Why sabre-toothed animals evolved again and again

New Scientist Feed - Thu, 01/09/2025 - 8:00am
Sabre teeth can be ideal for puncturing the flesh of prey, which may explain why they evolved in different groups of mammals at least five times
Categories: Science

Keeping space tidy should become a global UN goal, say researchers

New Scientist Feed - Thu, 01/09/2025 - 8:00am
The United Nations has 17 sustainable development goals that all member states have signed up to in an effort to balance economics and the environment - and now researchers say we need a new one to ensure we keep space junk under control
Categories: Science

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