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Lab-grown 'mini-guts' could help in development of new and more personalized treatments for Crohn's disease

Matter and energy from Science Daily Feed - Mon, 06/10/2024 - 5:29pm
Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients. The researchers say these mini-guts could in future be used to identify the best treatment for an individual patient, allowing for more precise and personalized treatments.
Categories: Science

If Gravity Can Exist Without Mass, That Could Explain Dark Matter

Universe Today Feed - Mon, 06/10/2024 - 2:37pm

Dark Matter is Nature’s poltergeist. We can see its effects, but we can’t see it, and we don’t know what it is. It’s as if Nature is playing tricks on us, hiding most of its mass and confounding our efforts to determine what it is.

It’s all part of the Universe’s “missing mass” problem. Actually, it’s our problem. The Universe is what it is. It’s our understanding of the Universe, mass, and gravity that’s the problem. And a solution is proving to be elusive.

Whatever the missing mass is or whatever causes the effects we observe, we have a placeholder name for it: dark matter. And it makes up 85% of the matter in the Universe.

Could dark matter be primordial black holes? Could it be axions? How about WIMPS? Are dark photons its force carrier? There’s lots of theoretical thought but no conclusion.

New research in the Monthly Notices of the Royal Astronomical Society says that our hunt for dark matter may be off-track. Instead of looking for a type of particle, the solution might lie in a type of topological defect found throughout the Universe that has its roots in the Universe’s early stages.

The new research is in a paper titled “The binding of cosmological structures by massless topological defects.” The author is Richard Lieu, a distinguished professor of physics and astronomy at the University of Alabama at Huntsville.

“There is then no need to perpetuate this seemingly endless search for dark matter.”

Dr. Richard Lieu, Professor, University of Alabama, Huntsville

As the paper’s title makes clear, dark matter has a binding effect on structures like galaxies. Astronomers know that galaxies don’t have enough measurable mass to hold themselves together. By measuring the mass of the stars and gas in galaxies, it became clear that the visible components of the galaxies don’t provide enough mass to hold themselves together. They should simply dissipate into their constituent stars and clouds of gas.

But galaxies don’t dissipate, and scientists have concluded that something is missing. Professor Lieu has another idea.

“My own inspiration came from my pursuit for another solution to the gravitational field equations of general relativity — the simplified version of which, applicable to the conditions of galaxies and clusters of galaxies, is known as the Poisson equation — which gives a finite gravitation force in the absence of any detectable mass,” said Lieu. “This initiative is in turn driven by my frustration with the status quo, namely the notion of dark matter’s existence despite the lack of any direct evidence for a whole century.”

An entire century is a long time in the age of modern science. It’s not surprising that Nature has the power to confound us, but it is somewhat surprising that very little progress has been made on the problem. Scientists have made great progress in understanding how dark matter influences the Universe’s large-scale structure, an impressive feat, but haven’t figured out what it is.

“The nature of dark matter (DM), defined specifically in this letter as an unknown component of the cosmic substratum responsible for the extra gravitational field that binds galaxies and clusters of galaxies, has been an enigma for more than a century,” Dr. Lieu writes in his paper.

Lieu’s work leans on phase transitions in the Universe. These are episodes when the state of matter in the Universe changes. Not locally but across the entire cosmos. One example is when the Universe cooled enough to allow the strong force to bind quarks into protons and neutrons.

Dr. Lieu contends that topological defects could have formed during one of these phase transitions. These defects can take the shape of shell-like compact regions where matter density is much higher. When arranged in concentric rings, these defects behave like gravity but don’t have mass.

“It is unclear presently what precise form of phase transition in the universe could give rise to topological defects of this sort,” Lieu says. “Topological effects are very compact regions of space with a very high density of matter, usually in the form of linear structures known as cosmic strings, although 2-D structures such as spherical shells are also possible. The shells in my paper consist of a thin inner layer of positive mass and a thin outer layer of negative mass; the total mass of both layers — which is all one could measure, mass-wise — is exactly zero, but when a star lies on this shell it experiences a large gravitational force pulling it towards the center of the shell.”

So, despite our inability to measure the mass, it’s there, and other objects respond to it. Mass warps space-time and affects even massless photons. That fact underlies our ability to use gravitational lensing. We use the mass of galaxy clusters in gravitational lensing. A set of spherical shells, as Lieu talks about, could cause the same effect.

This illustration shows the gravitational lensing phenomenon. Astronomers use it to study very distant and very faint objects. Note that the scale has been greatly exaggerated in this diagram. In reality, the distant galaxy is much further away and much smaller. Image Credit: NASA, ESA & L. Calcada

“Gravitational bending of light by a set of concentric singular shells comprising a galaxy or cluster is due to a ray of light being deflected slightly inwards — that is, towards the center of the large-scale structure, or the set of shells — as it passes through one shell,” Lieu notes. “The sum total effect of passage through many shells is a finite and measurable total deflection which mimics the presence of a large amount of dark matter in much the same way as the velocity of stellar orbits.”

Since astronomers measure galaxy and galaxy cluster masses by measuring the light they deflect and the way they affect the orbit of stars, astronomers could be measuring topological defects rather than particles that comprise dark matter.

“Both the deflection of light and stellar orbital velocities is the only means by which one gauges the strength of the gravitational field in a large-scale structure, be it a galaxy or a cluster of galaxies,” Dr. Lieu says. “The contention of my paper is that at least the shells it posits are massless. There is then no need to perpetuate this seemingly endless search for dark matter.”

In 2022, researchers discovered a giant arc in the sky. It spans 1 Gigaparsec and is nearly symmetrical. It’s one of several large-scale structures that seems to go against the Standard Model and the Cosmological Principle it’s based on.

These are three separate data images of the Giant Arc discovered in 2022. The paper provides details. Image Credit: Lopez et al. 2022, 10.1093/mnras/stac2204

“The observation of giant arcs and rings could lend further support to the proposed alternative to the DM model,” Lieu writes in his paper. He also points out that the shells he proposes needn’t be a complete sphere.

If these shells exist, their alignment would also govern the formation and shape of galaxies and clusters. Future research will determine exactly how these shells form. “This paper does not attempt to tackle the problem of structure formation,” Lieu says. In fact, Lieu acknowledges that there’s currently no way to even observe how they might form.

“A contentious point is whether the shells were initially planes or even straight strings, but angular momentum winds them up. There is also the question of how to confirm or refute the proposed shells by dedicated observations,” Lieu says.

An experienced scientist, Lieu knows the limits of what he’s proposing.

“Of course, the availability of a second solution, even if it is highly suggestive, is not by itself sufficient to discredit the dark matter hypothesis — it could be an interesting mathematical exercise at best,” Lieu concludes. “But it is the first proof that gravity can exist without mass.”

The post If Gravity Can Exist Without Mass, That Could Explain Dark Matter appeared first on Universe Today.

Categories: Science

Lone Star State: Tracking a low-mass star as it speeds across the Milky Way

Space and time from Science Daily Feed - Mon, 06/10/2024 - 2:10pm
Astronomers have discovered a rare hypervelocity L subdwarf star racing through the Milky Way. More remarkably, this star may be on a trajectory that causes it to leave the Milky Way altogether.
Categories: Science

NASA's Webb opens new window on supernova science

Space and time from Science Daily Feed - Mon, 06/10/2024 - 2:10pm
Peering deeply into the cosmos, NASA's James Webb Space Telescope is giving scientists their first detailed glimpse of supernovae from a time when our universe was just a small fraction of its current age. A team using Webb data has identified 10 times more supernovae in the early universe than were previously known. A few of the newfound exploding stars are the most distant examples of their type, including those used to measure the universe's expansion rate.
Categories: Science

Researchers engineer new approach for controlling thermal emission

Matter and energy from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
If a material absorbs light, it will heat up. That heat must go somewhere, and the ability to control where and how much heat is emitted can protect or even hide such devices as satellites. An international team of researchers has published a novel method for controlling this thermal emission in Science.
Categories: Science

Researchers engineer new approach for controlling thermal emission

Space and time from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
If a material absorbs light, it will heat up. That heat must go somewhere, and the ability to control where and how much heat is emitted can protect or even hide such devices as satellites. An international team of researchers has published a novel method for controlling this thermal emission in Science.
Categories: Science

Novel radiotracer produces high quality images of 'Alzheimer's disease of the heart'

Matter and energy from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
A newly developed radiotracer can generate high quality and readily interpretable images of cardiac amyloidosis, a condition referred to as the 'Alzheimer's disease of the heart.' As the first amyloid-specific and pan-amyloid binding radiotracer designed for planar and SPECT/CT imaging, 99mTc-p5+14 could play an important role in early detection and treatment of cardiac amyloidosis.
Categories: Science

Four-legged, dog-like robot 'sniffs' hazardous gases in inaccessible environments

Computers and Math from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
Nightmare material or truly man's best friend? A team of researchers equipped a dog-like quadruped robot with a mechanized arm that takes air samples from potentially treacherous situations, such as an abandoned building or fire. The robot dog walks samples to a person who screens them for potentially hazardous compounds.
Categories: Science

Four-legged, dog-like robot 'sniffs' hazardous gases in inaccessible environments

Matter and energy from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
Nightmare material or truly man's best friend? A team of researchers equipped a dog-like quadruped robot with a mechanized arm that takes air samples from potentially treacherous situations, such as an abandoned building or fire. The robot dog walks samples to a person who screens them for potentially hazardous compounds.
Categories: Science

Protocol for creating 'wired miniature brains'

Computers and Math from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
Researchers have developed -- and shared -- a process for creating brain cortical organoids -- essentially miniature artificial brains with functioning neural networks.
Categories: Science

Protocol for creating 'wired miniature brains'

Matter and energy from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
Researchers have developed -- and shared -- a process for creating brain cortical organoids -- essentially miniature artificial brains with functioning neural networks.
Categories: Science

Advanced AI-based techniques scale-up solving complex combinatorial optimization problems

Computers and Math from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
A framework based on advanced AI techniques can solve complex, computationally intensive problems faster and in a more more scalable way than state-of-the-art methods, according to a new study.
Categories: Science

Hubble finds surprises around a star that erupted 40 years ago

Space and time from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
Astronomers have used new data from NASA's Hubble Space Telescope and the retired SOFIA (Stratospheric Observatory for Infrared Astronomy) as well as archival data from other missions to revisit one of the strangest binary star systems in our galaxy -- 40 years after it burst onto the scene as a bright and long-lived nova. A nova is a star that suddenly increases its brightness tremendously and then fades away to its former obscurity, usually in a few months or years.
Categories: Science

Researchers demonstrate the first chip-based 3D printer

Computers and Math from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
Researchers have demonstrated the first chip-based 3D printer, a tiny device that emits reconfigurable beams of visible light into a well of resin that rapidly cures into a solid shape. The advance could enable a 3D printer small enough to fit in the palm of a person's hand.
Categories: Science

Researchers demonstrate the first chip-based 3D printer

Matter and energy from Science Daily Feed - Mon, 06/10/2024 - 2:09pm
Researchers have demonstrated the first chip-based 3D printer, a tiny device that emits reconfigurable beams of visible light into a well of resin that rapidly cures into a solid shape. The advance could enable a 3D printer small enough to fit in the palm of a person's hand.
Categories: Science

A New Way to Search for the First Stars in the Universe

Universe Today Feed - Mon, 06/10/2024 - 1:21pm

Observing the earliest stars is one of the holy Grails of astronomy. Now, a team at the University of Hong Kong led by astronomer Jane Lixin Dai is proposing a new method for detecting them. If it works, the approach promises to open a window on the origin of the cosmos itself.

The earliest stars in the Universe formed very soon after the Big Bang. Astronomers call them “Population III” (or Pop III) stars. They’re different from the Sun and other stars in the modern cosmos for a variety of reasons. They formed mainly from the hydrogen and helium in the newborn cosmos. From there, they grew to outrageous sizes and masses very quickly. That growth had a price. Those stars had very short lives because they blew through their core fuels very quickly. However, fusion at their cores and the circumstances of their deaths created the first elements heavier than hydrogen and helium. Those new elements seeded the next generations of stars.

Population III stars were the Universe’s first stars. They were extremely massive, luminous stars, and many of them exploded as supernovae. Image Credit: DALL-E

So, why can’t we detect these early stellar behemoths? For one thing, they existed too far away, too early in history, and their light is very faint. That’s not to say they are undetectable. Astronomers just need advanced methods and technology to spot them.

How to “See” the First Stars

Professor Dai’s team just published a study that suggests a connection between these first stars and nearby black holes. In short, they looked at what happens when a Pop III star interacts with a black hole. Essentially, it gets torn to shreds and gobbled up. For example, the supermassive one at the heart of our Milky Way Galaxy—called Sagittarius A*— does this. It has a regular habit of ripping apart stars that wander too close. When such a tidal disruption event (TDE) happens, it releases huge amounts of radiation. If the same thing happens in another galaxy—no matter how far away—the light from the event is detectable. As it turns out these tidal disruption event flares have interesting and unique properties used to infer the existence of the ancient Pop III stars.

The alien star S0-6 is spiraling toward Sagittarius A*, the Milky Way’s central supermassive black hole. S0-6 likely came from another galaxy and it may get gobbled up or torn up by interactions with the supermassive black hole. Courtesy: Miyagi University of Education/NAOJ.

“As the energetic photons travel from a very faraway distance, the timescale of the flare will be stretched due to the expansion of the Universe. These TDE flares will rise and decay over a very long period of time, which sets them apart from the TDEs of solar-type stars in the nearby Universe,” said Dai.

In addition, the expansion of the Universe stretches the wavelengths of light from the flares, according to Dai’s colleague, Rudrani Kar Chowdhury. “The optical and ultraviolet light emitted by the TDE will be transferred to infrared emissions when reaching the Earth,” Chowdhury said. Those emissions are exactly the kind of light new generations of telescopes are built to observe.

Searching for First Stars with Advanced Telescopes

This detection method is right up the alley of the JWST and the upcoming Nancy Grace Roman telescopes. Both are optimized to sense dim, distant objects via infrared wavelengths. They should be able to search out the stretched light from those long-gone Pop III stars unfortunate enough to encounter a black hole. In particular, the Roman telescope will use its wide-field instrument to gather the faint infrared light from stars born at the earliest epochs of cosmic time.

Artist’s impression of the Nancy Grace Roman space telescope (formerly WFIRST). Credit: NASA/GSFC

Astronomers generally accept that these first stars formed perhaps as early as a hundred million years after the Big Bang. That’s when overly dense regions filled with hydrogen and helium began to experience gravitational collapse. The stars that formed in those first birth crèches were purely hydrogen and helium—in other words, they were “metal-free”. They lived perhaps a few million years before exploding as cataclysmic supernovae. (By comparison, the Sun has existed for some 4.5 billion years and has another few billion years left before it becomes a red giant and then a white dwarf.) The heavier elements created inside those first stars got blasted out to space, enriching the nearby molecular clouds with infusions of carbon, oxygen, nitrogen, and other elements. Some of the largest first stars could have collapsed directly to form black holes.

Finding these first stars and their emitted light (particularly from possible interactions with early black holes) will give astronomers amazing insight into conditions in the early Universe. Even though those stars are long gone, JWST, Roman, and other telescopes can look back in time and see their dim, infrared light. If Dai’s method works, those telescopes could be responsible for the discovery of tens of Pop III stars each year.

For More Information

HKU Astrophysicists Discover a Novel Method for Hunting the First Stars
Detecting Population III Stars through Tidal Disruption Events in the Era of JWST and RomanNancy Grace Roman Space Telescope

The post A New Way to Search for the First Stars in the Universe appeared first on Universe Today.

Categories: Science

Landing on Pluto May Only Be A Hop Skip and Jump Away

Universe Today Feed - Mon, 06/10/2024 - 11:54am

There are plenty of crazy ideas for missions in the space exploration community. Some are just better funded than others. One of the early pathways to funding the crazy ideas is NASA’s Institute for Advanced Concepts. In 2017 and again in 2021, it funded a mission study of what most space enthusiasts would consider only a modestly ambitious goal but what those outside the community might consider outlandish—landing on Pluto.

Two major questions stand out in the mission design: How would a probe arriving at Pluto slow down, and what kind of lander would be useful on Pluto itself? The answer to the first is one that is becoming increasingly common on planetary exploration missions: aerobraking.

Pluto has an atmosphere, albeit sparse, as confirmed by the New Horizons mission that whizzed past in 2015. One advantage of the minor planet’s relatively weak gravity is that its low-density atmosphere is almost eight times larger than Earth’s, providing a much bigger target for a fast incoming aerobraking craft to aim for.

Fraser discusses future missions to Pluto.

Much of the NIAC Phase I project was focused on the details of that aerobraking system, called the Enveloping Aerodynamic Decelerator (EAD). Combined with a lander, that system makes up the “Entrycraft” that the mission is designed around. Ostensibly, it could alternatively contain an orbiter, and there are plenty of other missions discussing how to insert an orbiter around Pluto. Hence, the main thrust of this paper is to focus on a lander.

After aerobraking and slowing down to a few tens of meters a second, from 14 km/s during its interplanetary cruise phase, the mission would drop its lander payload, then rest on the surface, only to rise again under its own power. The answer to the second question of what kind of lander would be useful on Pluto is – a hopper.

Hoppers have become increasingly popular as an exploration tool everywhere, from the Moon to asteroids. Some apparent advantages would include visiting a wide array of interesting scientific sites and not having to navigate tricky land-based obstacles. Ingenuity, the helicopter that accompanied Perseverance paved the way for the idea, but in other words, the atmosphere isn’t dense enough to support a helicopter. So why not use the current favorite method of almost all spacecraft – rockets?

Fraser discusses the results from New Horizons.

A hopper would fire its onboard thrusters to reach the area on Pluto’s surface and then land elsewhere. It could then do some science at its new locale before taking off and doing so again somewhere else. The NIAC Phase I Final Report describes five main scientific objectives of the mission, including understanding the surface geomorphology and running some in-situ chemical analysis. A hopper structure would enable those goals much better than a traditional rover at a relatively low weight cost since Pluto’s gravity is so weak.

Other objectives of the report include mathematical calculations of the trajectory, including the aerobraking itself and the stress and strain it would have on the materials used in the system. The authors, who primarily work for Global Aerospace Corporation and ILC Dover, two private companies, also updated the atmospheric models of Pluto with new New Horizons data, which they then fed into the aerobraking model they used. Designing the lander/hopper, integrating all the scientific and navigation components, and estimating their weights were also part of Phase I.

The original launch window for the mission was planned as 2029 back in 2018, though now, despite receiving a Phase II NIAC grant in 2021, that launch window seems wildly optimistic. Since the mission would require a gravity assist from Jupiter, the next potential launch window would be 2042, with a lander finally reaching the surface of Pluto in the 2050s. That later launch window is likely the only feasible one for the mission, so we might have to wait almost 30 years to see if it will come to fruition. Sometimes crazy ideas take patience – we’ll see if the mission team has enough of that to push it onto the surface of one of the most interesting minor planets in the solar system.

Learn More:
B. Goldman – Pluto HopSkip, and Jump
UT – NASA is Now Considering a Pluto Orbiter Mission
UT – Should We Send Humans to Pluto?
UT – New Horizons Team Pieces Together the Best Images They Have of Pluto’s Far Side

Lead Image:
Artist’s depiction of the Pluto Lander mission design.
Credit- B. Goldman / Global Aerospace Corporation

The post Landing on Pluto May Only Be A Hop Skip and Jump Away appeared first on Universe Today.

Categories: Science

Webb telescope reveals asteroid collision in neighboring star system

Space and time from Science Daily Feed - Mon, 06/10/2024 - 11:03am
Astronomers have captured what appears to be a snapshot of a massive collision of giant asteroids in Beta Pictoris, a neighboring star system known for its early age and tumultuous planet-forming activity.
Categories: Science

Researchers create skin-inspired sensory robots to provide medical treatment

Computers and Math from Science Daily Feed - Mon, 06/10/2024 - 11:03am
Scientists have created innovative soft robots equipped with electronic skins and artificial muscles, allowing them to sense their surroundings and adapt their movements in real-time.
Categories: Science

Researchers create skin-inspired sensory robots to provide medical treatment

Matter and energy from Science Daily Feed - Mon, 06/10/2024 - 11:03am
Scientists have created innovative soft robots equipped with electronic skins and artificial muscles, allowing them to sense their surroundings and adapt their movements in real-time.
Categories: Science

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