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AI could predict breast cancer risk via 'zombie cells'

Computers and Math from Science Daily Feed - Wed, 09/25/2024 - 3:35pm
Women worldwide could see better treatment with new AI technology which enables better detection of damaged cells and more precisely predict the risk of getting breast cancer, shows new research.
Categories: Science

How much should we worry about the health effects of microplastics?

New Scientist Feed - Wed, 09/25/2024 - 3:06pm
A flurry of studies has found microplastics in nearly every organ in the human body, from the brain to the testicles. But very few have revealed whether these tiny bits of plastic impact our health
Categories: Science

We now know who was cannibalised on the doomed Franklin expedition

New Scientist Feed - Wed, 09/25/2024 - 3:00pm
DNA and genealogical evidence reveal, for the first time, the identity of cannibalised remains recovered from the Franklin expedition
Categories: Science

Dinosaurs may have run like emus by keeping one foot on the ground

New Scientist Feed - Wed, 09/25/2024 - 12:00pm
It seems to be more energy efficient for emus to keep one foot on the ground when running at a moderate pace, and the same may have been true for dinosaurs
Categories: Science

How special is the Milky Way Galaxy?

Space and time from Science Daily Feed - Wed, 09/25/2024 - 11:40am
The SAGA Survey just published three new research articles that provide us with new insights into the uniqueness of our own Milky Way Galaxy after completing the census of 101 satellite systems similar to the Milky Way's.
Categories: Science

Researchers innovate sustainable metal-recycling method

Matter and energy from Science Daily Feed - Wed, 09/25/2024 - 11:40am
A research team has developed a method to recycle valuable metals from electronic waste more efficiently while significantly reducing the environmental impact typically associated with metal recycling.
Categories: Science

Mars' missing atmosphere could be hiding in plain sight

Matter and energy from Science Daily Feed - Wed, 09/25/2024 - 11:39am
New research suggests Mars' missing atmosphere -- which dramatically diminished 3.5 billion years ago -- could be locked in the planet's clay-covered crust. Water on Mars could have set off a chain reaction that drew CO2 out of the atmosphere and converted it into methane within clay minerals.
Categories: Science

Mars' missing atmosphere could be hiding in plain sight

Space and time from Science Daily Feed - Wed, 09/25/2024 - 11:39am
New research suggests Mars' missing atmosphere -- which dramatically diminished 3.5 billion years ago -- could be locked in the planet's clay-covered crust. Water on Mars could have set off a chain reaction that drew CO2 out of the atmosphere and converted it into methane within clay minerals.
Categories: Science

Space Travel Weakens the Heart, New Study Finds

Universe Today Feed - Wed, 09/25/2024 - 11:37am

It’s no secret that spending extended periods in space takes a toll on the human body. For years, NASA and other space agencies have been researching the effects of microgravity on humans, animals, and plants aboard the International Space Station (ISS). So far, the research has shown that being in space for long periods leads to muscle atrophy, bone density loss, changes in vision, gene expression, and psychological issues. Knowing these effects and how to mitigate them is essential given our future space exploration goals, which include long-duration missions to the Moon, Mars, and beyond.

However, according to a recent experiment led by researchers at Johns Hopkins University and supported by NASA’s Johnson Space Center, it appears that heart tissues “really don’t fare well in space” either. The experiment consisted of 48 samples of human bioengineered heart tissue being sent to the ISS for 30 days. As they indicate in their paper, the experiment demonstrates that exposure to microgravity weakens heart tissue and weakens its ability to maintain rhythmic beats. These results indicate that additional measures must be taken to ensure humans can maintain their cardiovascular health in space.

The study was led by Deok-Ho Kim and his colleagues from the Department of Biomedical Engineering at Johns Hopkins University (BME-JHU) and the JHU Center for Microphysiological Systems. They were joined by researchers from UC Boulder’s Ann and HJ Smead Department of Aerospace Engineering Sciences, the Institute for Stem Cell & Regenerative Medicine (ISCRM) and the Center for Cardiovascular Biology at the University of Washington, the Stanford Institute for Stem Cell & Regenerative Medicine, BioServe Space Technologies, and NASA’s Johnson Space Center. The paper that details their findings was published yesterday (September 23rd) in the Proceedings of the National Academy of Sciences.

Heart tissues within one of the launch-ready chambers. Credit: Jonathan Tsui

Previous research has shown that astronauts returning to Earth from the ISS suffer from a myriad of health effects consistent with certain age-related conditions, including reduced heart muscle function and irregular heartbeats (arrhythmias), most of which will dissipate over time. However, none of this research has addressed what happens at the cellular and molecular level. To learn more about these effects and how to mitigate them, Kim and his colleagues sent an automated “heart-on-a-chip” platform to the ISS for study.

To create this payload, the team relied on human-induced pluripotent stem cells (iPSCs), which can become many types of cells, to produce cardiomyocytes (heart muscle cells). These resulting tissues were placed in a miniaturized bioengineered tissue chip designed to mimic the environment of an adult human heart. The chips would then collect data on how the tissues would rhythmically contract, imitating how the heart beats. One set of biochips was launched aboard the SpaceX CRS-20 mission to the ISS in March 2020, while another was kept on Earth as a control group.

Once on the ISS, astronaut Jessica Meir tended the experiment, changing the liquid nutrients surrounding the tissues once each week while preserving tissue samples at specific intervals so gene readout and imaging analyses could be conducted upon their return to Earth. Meanwhile, the experiment sent real-time data back to Earth every 30 minutes (for 10 seconds at a time) on the tissue samples’ contractions and any irregular beating patterns (arrhythmias).

“An incredible amount of cutting-edge technology in the areas of stem cell and tissue engineering, biosensors and bioelectronics, and microfabrication went into ensuring the viability of these tissues in space,” said Kim in a recent Hub news release.

When the tissue chambers returned to Earth, he and his colleagues continued to maintain and collect data from the samples to see if there was any change in their abilities to contract. In addition to losing strength, the muscle tissues developed arrhythmias, consistent with age-related heart conditions. In a healthy human heart, the time between beats is about a second, whereas the tissue samples lasted nearly five times as long – though they returned to nearly normal once returned to Earth.

The team further found that the tissue cell’s protein bundles that help them contract (sarcomeres) were shorter and more disordered than those of the control group, another symptom of heart disease. What’s more, the mitochondria in the tissue samples grew larger and rounder and lost the characteristic folds that help them produce and use energy. Lastly, the gene readout in the tissues showed increased gene production related to inflammation and an imbalance of free radicals and antioxidants (oxidative stress).

This is not only consistent with age-related heart disease but also consistently demonstrated in astronauts’ post-flight checks. The team says these findings expand our scientific knowledge of microgravity’s potential effects on human health in space and could also advance the study of heart muscle aging and therapeutics on Earth. In 2023, Kim’s lab followed up on this experiment by sending a second batch of tissue samples to the ISS to test drugs that could help protect heart muscles from the effects of microgravity and help people maintain heart function as they age.

Meanwhile, the team continues to improve its tissue-on-a-chip system and has teamed up with NASA’s Space Radiation Laboratory to study the effects of space radiation on heart muscles. These tests will assess the threat solar and cosmic rays pose to cardiovascular health beyond Low Earth Orbit (LEO), where Earth’s magnetic field protects against most space radiation.

Further Reading: John Hopkins University, PNAS

The post Space Travel Weakens the Heart, New Study Finds appeared first on Universe Today.

Categories: Science

The chemistry behind making a perfect caramel sauce

New Scientist Feed - Wed, 09/25/2024 - 11:00am
Bake Off finalist and chemical biologist Josh Smalley shares his recipe for the perfect caramel sauce with Catherine de Lange
Categories: Science

Stellar views of some of the most spectacular sights in the universe

New Scientist Feed - Wed, 09/25/2024 - 11:00am
These dazzling images taken by NASA's Hubble Space Telescope are from the upcoming book Cosmos: Explore the wonders of the universe, which has a foreword by astrophysicist Becky Smethurst
Categories: Science

Samantha Morton stars in dystopian docudrama 2073

New Scientist Feed - Wed, 09/25/2024 - 11:00am
What if tech bros ruled the world, asks Asif Kapadia's 2073. This docudrama is captivating and disturbing, but lacks enough heft to stand out
Categories: Science

How genetically modified crops could feed us and help safeguard nature

New Scientist Feed - Wed, 09/25/2024 - 11:00am
There has been plenty of controversy over GM crops, but if deployed well they could have a positive environmental impact, says Graham Lawton
Categories: Science

Why does hair pulling hurt? Blame your myelinated nociceptors

New Scientist Feed - Wed, 09/25/2024 - 11:00am
Feedback explores the painstaking science of hair-pulling, and learns that experts have discovered that its effects can range from "hot-burning" to "aching"
Categories: Science

If we reassessed what maths is, perhaps it wouldn't make us so anxious

New Scientist Feed - Wed, 09/25/2024 - 11:00am
Fear of maths has been around for at least a century. Here are some ways to overcome it, says Sarah Hart, professor emerita of mathematics at Birkbeck, University of London
Categories: Science

How colonialism and industrialisation fuelled the climate crisis

New Scientist Feed - Wed, 09/25/2024 - 11:00am
There can be no victory in a war against nature, says Sunil Amrith in The Burning Earth, a must-read history of our environmental crisis
Categories: Science

Geoengineering is now essential to saving the Arctic's ice

New Scientist Feed - Wed, 09/25/2024 - 11:00am
If we want to preserve the dwindling ice in the Arctic, cutting our emissions is no longer enough – we also need to use geoengineering to refreeze this precious ecosystem
Categories: Science

Will Comet A3 Tsuchinshan-ATLAS Shine Brighter Than Expected?

Universe Today Feed - Wed, 09/25/2024 - 10:53am

Now is the time to catch Comet A3-Tsuchinshan-ATLAS at dawn.

The window is now open. If skies are clear, set your alarm heading into this weekend to see Comet C/2023 A3 Tsuchinshan-ATLAS at dawn. We’re already seeing great views of the comet this week from southern observers and astronauts aboard the International Space Station. The visibility window is now even creeping up to the southern tier latitudes of the contiguous United States (CONUS). If fortune favors us, the comet could hit an easy naked eye magnitude +2 by next week, and forward scattering could even boost this into negative magnitudes… the rare term ‘daytime comet’ is even getting kicked around a bit in cometwatching circles.

But the span to see this comet will be brief indeed. For most northern hemisphere observers, the comet will be a bashful one, never reaching much more than 10 degrees above the eastern horizon about 45 minutes before sunrise on the week centered around September 29th.

Exposures of Comet A3 against the brightening dawn. Credit: Chris Schur The Story of Comet A3 Tsuchinshan-ATLAS Thus Far

We wrote about prospects for this comet for Universe Today previously just last month. China’s Tsuchinshan (Purple Mountain) observatory and the automated ATLAS (Asteroid Terrestrial impact Last Alert System) survey discovered the comet on January 9th, 2023. I’ve seen the name abbreviated to simply ‘Comet A3’ or ‘Comet T-ATLAS’ in discussions on keystroke-conservative social media.

Likely a first-time visitor to the inner solar system from the distant Oort Cloud, the comet is on an orbit measured in millions of years. This may also be the one and only appearance of the comet in the inner solar system. That’s a good thing, in terms of dynamics and activity, as the comet may have never experienced the heat of the inner solar system in the past. The comet could well head towards permanent ejection from the solar system after perihelion.

Key dates coming right up include when the comet reaches perihelion this coming Friday on September 27th at 0.391 Astronomical Units (AU, 36.4 million miles or 58.6 million kilometers) from the Sun, just interior to Mercury’s aphelion point. The comet then makes its closest Earth approach on October 12th, at 0.556 AU distant.

Comet A3 Tsuchinshan-ATLAS will become more difficult to catch after October 7th, as it heads in to the Solar Heliospheric Observatory’s (SOHO) LASCO C3 field of view and approaches less than 15 degrees elongation from the Sun. The comet makes a second evening reappearance mid-month, which will most likely be less than favorable as it heads away from us and back out of the inner solar system. We could, however, see something interesting in late October (if the comet survives perihelion) as the tail precedes ahead of the outbound comet.

Chris Schur caught the comet from Payson, Arizona (with a narrow 10 minute window!) on the morning of September 23rd. Credit: Chris Schur. How the Comet is Performing Now

The comet seemed to be headed towards the long rolls of ‘great comets that weren’t’ this past summer, as it stalled at +10th magnitude. Now, the trend seems to have shifted, as the comet is over-performing versus expectations. As of writing this, the comet stands at +3rd magnitude and is rapidly brightening.

We’re already seeing signs of two tails (one dust and one ion) forming in this week’s images of the comet. Forward scattering may help boost the visibility of the comet next week, as all those dust particles reach a maximum illumination angle as seen from our Earthly vantage point in early October. The comet’s orbit passes edge-on from our vantage point on October 14th. The comet will seem to hang stationary low in the dawn next week, as it loops towards us, and then crosses between the Earth and the Sun.

Comet T-ATLAS as imaged from Tivoli Farm, Namibia on September 22nd (note the fan of the comet’s second tail off to the left). Credit: Gerald Rhemann. How to See the Comet

The October apparition will be a tricky one for sure. A good strategy is to use binoculars and start sweeping low to the eastern horizon about an hour before local sunrise. The +1st magnitude star Regulus (Alpha Leonis) will make a good ‘guide star’ to find the comet. The star will be about an outstretched hand’s width to the observer’s lower right. The comet pairs with the slim waning crescent Moon on the morning of September 30th, making for a grand photo-op. That same Moon is headed towards an annular solar eclipse on October 2nd.

The view on the morning of September 30th. Credit: Starry Night Edu Software.

Clouded out? We feel your frustration here in eastern Tennessee, as clouds from approaching hurricane Helene move inland this coming weekend. Astronomer Gianluca Masi will also carry the comet live on the evening of October 9th.

Comet C/2023 A3 Tsuchinshan-ATLAS from September 24th. Credit: The Virtual Telescope Project.

“It (Comet T-ATLAS) survived and so far, it looks brighter than expected.” Astrophotographer Eliot Herman told Universe Today. “I still don’t think it will be amazing when it can be seen when dark enough… I am thinking maybe March 2013 Comet (C/2011 L4) PanSTARRS level – which was visible to the eye and pretty nice with a camera.”

We can only hope for a bright comet as depicted by astronomer Charles Piazzi Smyth’s painting of the Great Daytime Comet of 1843:

Smyth’s painting, at the Greenwich Maritime Museum. Credit: Dave Dickinson. The Comet From the ISS

Astronauts aboard the International Space Station already caught the comet from their vantage point in low Earth orbit this week. NASA astronaut Matthew Dominick produced this fine animation:

Comet A3 Tsuchinshan-ATLAS is teasing us with the recent memories of two other dawn comets. Remember P1 McNaught in 2006-2007 and W3 Lovejoy in 2011-2012? Both beat the odds, and went on to become fine comets, ahead of expectations.

Comet McNaught imaged from Villa Alemana, Chile in January 2007. Credit: Garcia Ruben/Wikimedia Commons/Public Domain.

As always with comets, a caveat is in order: several factors will conspire against your cometary quest. First: as noted, the comet will appear very low to the horizon. This means it will fight against the thick murk of the atmosphere and the brightening twilight sky. Secondly, comets are intrinsically dark objects, with a low surface brightness or albedo… remember Rosetta’s views of Comet 67P Churumov-Gerasimenko? Lastly, like deep sky objects, all of that precious magnitude gets dispersed over an apparent surface area. This makes a +2 magnitude comet much fainter looking versus a +2nd magnitude star. During F3 NEOWISE’s 2020 apparition, I could juuuust start to convince myself that it was naked eye when it reached around +1st magnitude.

Comet C/2023 A3 (Tsuchinshan-ATLAS) is finally here ! ???I captured this image this morning at 09:22 UTC from @LCOAstro in Atacama desert in Chile ?? The view was absolutely spectacular ! The clouds were constantly moving just above the horizon, but we got really lucky when the… pic.twitter.com/AoClHkatFr

— Yuri Beletsky (@YBeletsky) September 24, 2024

NEOWISE… or Nishimura?

We had two recent comets perform very similar to Comet A3 Tsuchinshan-ATLAS. In 2020, Comet F3 NEOWISE became a fine naked eye comet at dawn, wowing early morning observers. On the flip side, 2023’s Comet P1 Nishimura flirted with naked eye brightness, but never really became a general crowd pleaser.

Clear skies on your hunt this coming week, to see what’s most likely to be the best comet of 2024.

The post Will Comet A3 Tsuchinshan-ATLAS Shine Brighter Than Expected? appeared first on Universe Today.

Categories: Science

Manganese cathodes could boost lithium-ion batteries

Matter and energy from Science Daily Feed - Wed, 09/25/2024 - 9:36am
Manganese is earth-abundant and cheap. A new process could help make it a contender to replace nickel and cobalt in batteries.
Categories: Science

Replacing hype about artificial intelligence with accurate measurements of success

Computers and Math from Science Daily Feed - Wed, 09/25/2024 - 9:35am
A new article notes that journal articles reporting how well machine learning models solve certain kinds of equations are often overly optimistic. The researchers suggest two rules for reporting results and systemic changes to encourage clarity and accuracy in reporting.
Categories: Science

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